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Efficacy and Safety of Two Dosages of Canrenone as Add-On Therapy in Hypertensive Patients Taking Ace-Inhibitors or Angiotensin II Receptor Blockers and Hydrochlorothiazide at Maximum Dosage in a Randomized Clinical Trial: The ESCAPE-IT Trial

机译：两种剂量的坎利酮作为高血压患者的附加疗法的有效性和安全性在随机临床试验中服用最大剂量的ace抑制剂或血管紧张素II受体阻滞剂和氢氯噻嗪：EsCapE-IT试验

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To evaluate the effects of canrenone as add-on therapy in patients already treated with angiotensin converting-enzyme inhibitors (ACE-I) or angiotensin II receptor blockers (ARBs) and hydrochlorothiazide at the maximum dosage (25 mg/day).

机译：在已经使用最大剂量（25毫克/天）的血管紧张素转化酶抑制剂（ACE-I）或血管紧张素II受体阻滞剂（ARB）和氢氯噻嗪治疗的患者中，评估烯睾丙内酯作为附加治疗的效果。

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Derosa, Giuseppe; Maffioli, Pamela; D'Avino, Maria; Sala, Carla; Mugellini, Amedeo; Vulpis, Vito; Felis, Salvatore; Guasti, Luigina; Sarzani, Riccardo; Bestetti, Alessandro; Vanasia, Massimo; Gaudio, Giovanni;
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1. A randomized, double-blind clinical trial of canrenone vs hydrochlorothiazide in addition to angiotensin II receptor blockers in hypertensive type 2 diabetic patients [J] . Giuseppe Derosa, Giovanni Gaudio, Gianfranco Pasini, Drug Design, Development and Therapy . 2018,第InaProgress期

机译：肾上腺素与氢氯噻嗪联合血管紧张素II受体阻滞剂对高血压2型糖尿病患者的随机，双盲临床试验
2. Randomized trial of an increased dose of calcium channel blocker or angiotensin II type 1 receptor blocker as an add-on intensive depressor therapy in type 2 diabetes mellitus patients with uncontrolled essential hypertension: the ACADEMIE Study [J] . Imaizumi Satoshi, Shiga Yuhei, Ogawa Masahiro, Heart and vessels: An international journal . 2019,第4期

机译：随机试验增加钙通道阻断剂或血管紧张素II型受体阻滞剂作为2型糖尿病患者的加入密集型减压患者，其具有不受控制的必需高血压：院校研究
3. Short-term add-on therapy with angiotensin receptor blocker for end-stage inotrope-dependent heart failure patients: B-type natriuretic peptide reduction in a randomized clinical trial [J] . Antonio C.p. Barretto, Euler C.o. Brancalh?o, Juliano N. Cardoso, Clinics . 2014,第5期

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4. Impact of Complementary Therapies via Mobile Technologies on Icelandic Same Day Surgical Patients' Reports of Anxiety, Pain and Self-Efficacy in Healing: A Randomized Controlled Trial in Process [C] . Margaret M. Hansen MEDINFO . 2013

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5. Recruitment, retention and compliance in randomized, phase III clinical trials involving obese patients diagnosed with type 2 Diabetes Mellitus with respect to weight loss practicum report. [D] . Mithani, Moez S. 2012

机译：涉及诊断为2型糖尿病的肥胖患者的有关减肥实践的随机III期临床试验中的招募，保留和依从性报告。
6. Efficacy and safety of two dosages of canrenone as add‐on therapy in hypertensive patients taking ace‐inhibitors or angiotensin II receptor blockers and hydrochlorothiazide at maximum dosage in a randomized clinical trial: The ESCAPE‐IT trial [O] . Giuseppe Derosa, Pamela Maffioli, Maria DAvino, -1

机译：在一项随机临床试验中以最大剂量服用ACEI或血管紧张素II受体阻滞剂和氢氯噻嗪的高血压患者两种剂量的佳耐乐酮作为附加疗法的疗效和安全性：ESCAPE-IT试验
7. A randomized, double-blind clinical trial of canrenone vs hydrochlorothiazide in addition to angiotensin II receptor blockers in hypertensive type 2 diabetic patients [O] . Giuseppe Derosa, Giovanni Gaudio, Gianfranco Pasini, 2018

机译：除血管紧张素II受体阻滞剂的高血压型2型糖尿病患者外，Canronone与羟氯噻嗪的随机，双盲临床试验

Efficacy and Safety of Two Dosages of Canrenone as Add-On Therapy in Hypertensive Patients Taking Ace-Inhibitors or Angiotensin II Receptor Blockers and Hydrochlorothiazide at Maximum Dosage in a Randomized Clinical Trial: The ESCAPE-IT Trial

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